Just a quick look at your pcb and it looks good
but maybe a few small changes.
I would have a trimpot to adjust duty cycle, in case you need less V or want to add regulation.
The driver transistors have high current 1-2A switching spikes, which can contaminate the SG3525's power or GND.
Look at Q3,Q4 collector traces running back to the IC. Instead I would run them to a seperate ground pin(s) - not connected to the SG3525 ground. This GND pin then connects to the output mosfet's source (the single point, star ground), so the high current path is not on your PCB.
Look at Q1,Q2 collector traces running back to the IC. Instead I would run the SG3525 +Vcc from a small R filter to have quiet power. See the 2.2R or 100uH inductor Elliot uses, it's important.
For the transformer, EC/ETD cores come in standard sizes, so you can measure the core height/width/thickness and have some idea.
I'm working on a 12V SMPS for car amp application and just got samples of
Mag Inc. ZP42915TC and ZP43615TC for 200-400W range. I got raped with $97 in shipping via UPS x-( for 6 cores - so watch out for that!